Perbandingan pemberian minyak kuning telur ayam dan bioplacenton terhadap gambaran histologi kulit
Article Sidebar
Published
May 7, 2021
How to Cite
1.
Widyawati R, Solfaine R, Kartika SariD, Shagita Y. Perbandingan pemberian minyak kuning telur ayam dan bioplacenton terhadap gambaran histologi kulit. VITEK : Bidang Kedokteran Hewan [Internet]. 7May2021 [cited 22Dec.2024];11(1):6-4. Available from: https://vitek-fkh.uwks.ac.id/index.php/jv/article/view/70
Section
Articles
Main Article Content
Abstract
This study was conducted to determine the comparison of re-epithelialization, granulation and the number of inflammatory cells infiltration between topical application of chicken yolk oil and bioplacenton on white rat (Rattus norvegicus) skin that has induced with second degree burn wound. This research was a laboratory experimental study using 18 male white rats divided into control positive (K+) group, bioplacenton (P1) and chicken yolk oil (P2). Observation of the re-epithelialization, granulation and inflammatory cells infiltration were carried out 14 days after the rat were induced with second degree burn wound. The necropcy was performed on the 14th day and then the skin organs were treated with HE staining and observed under a microscope. Data analysis was performed using Kruskal-Wallis followed by Mann Whitney. The results of the analysis showed that K + had significantly different results (P <0.05) compared to P1 and P2 in the scores of re-epithelialization, granulation and the number of inflammatory cell infiltrations. P1 and P2 were not significantly different (P> 0.05). In this study, it can be concluded that chicken egg yolk has a comparable effect with bioplacenton toward the score of re-epithelialization, granulation and the number of inflammatory cell infiltration.
Keywords:
Chicken yolk oil, Bioplacenton, Re-epithelialization, Granulation, Inflammatory cell infiltrations
References
Sandhiutami, Ni Made Dwi, Yesi Desmiaty, Nuryenti, 2018. Efek Pemberian Ekstrak Etanol Daun Jati Belanda (Guazuma ulmifolia Lamk.) Terhadap Penyembuhan Luka Bakar Derajat IIA Pada Tikus Putih. Fakultas Farmasi. Universitas Pancasila.
Lee, K. C., Kavita Joory, Naiem S. Moiemen, 2014. History of burns: The past, present and the future. Burns & Trauma, October 2014, Vol 2, Issue 4.
Setiawan, M. Riza, Afiana Rohmani, Ika Dyah Kurniati, Kanti Ratnaningrum, Rochman Basuki, 2015. Buku Ajar Ilmu Bedah. Fakultas Kedokteran. Universitas Muhammadiyah Semarang.
KalbeMed, 2020. Bioplacenton®. https://kalbemed.com/Products-Diseases/Products/Read-Product-Article/ArtMID/458/ArticleID/179/BIOPLACENTON. Diakses Mei 2020
Hu, T. M., Tsuo-Hung Lan and El-Wui Loh, 2012. An Emerging Complimentary Medicine-Yolk Oil Made from Heating Method. Journal of Traditional and Complementary Medicine Vol. 2, No. 2, pp. 202-203.
Madan, K. dan Sanju Nanda, 2016. Hen egg yolk oil: A potential source of bioavailable lutein and zeaxanthin for skin and sun protection. World Journal Pharmaceutical Sciences. 5(1): 71-80.
Guo, S. dan L.A. DiPietro, 2010. Factors Affecting Wound Healing. Center for Wound Healing and Tissue Regeneration, Department of Periodontics, College of Dentistry. University of Illinois at Chicago.
Tiwari, V.K., 2019. Burn wound: How it differs from other wounds?. Department of Burns and Plastic Surgery, VMMC and Safdarjung Hospital, New Delhi, India.
Alhasyimi, Ananto A., 2016. INDUKSI RE-EPITELISASI PADA PROSES PENYEMBUHAN LUKA GINGIVA OLEH APLIKASI TOPIKAL EKSTRAK DAUN SAGE (Salvia officinalis L.) KONSENTRASI 50% (Kajian In Vivo Pada Tikus Sprague Dawley. Bagian Ortodonsi, Fkg Universitas Gadjah Mada, Yogyakarta
Gonzales, Ana C.O., Zilton A.A., Tila F.C. Alena R.A.P.M., 2017. Wound healing-A ltiteratire review. Anais Brasileiros de Dermatologia.
Kartikaningtyas, Aqilla T., Prayitno dan Sri P. L., 2015. Pengaruh Aplikasi Gel Ekstrak Kulit Citrus Sinensis terhadap Epitelisasi pada Penyembuhan Luka Gingiva Tikus Sprague Dawley. Majalah Kedokteran Gigi Indonesia.
Nasution, Abdillah I., 2016. BUKU AJAR BIOMOLEKULER untuk Ilmu Kedokteran Dasar. Syiah Kuala University Press
Batthacharya, Geetika K., 2017. Pathology for Dental Students (Second Edition). ELSEVIER.
Serhan, Charles N., Peter A.W., Derek W.G., 2010. Fundamentals of Inflamation. Cambridge University Press.
Anderson, James M., 2013. Inflamation, Wound Healing and the Foreign-Body Response dalam Biomaterials Science (Third Edition). Elsevier Academic Press
Anderson, James M., 2019. Biocompatibility and Bioresponse to Biomaterials dalam Principles of Regenerative Medicine (Third Edition). Elsevier Academic Press
Ivanalee, S. K., Ira Sari Y., Maya Nurwartanti Y., Nusdianto Triakoso, Iwan Sahrial H., Amung Logam S., 2018.
Efektivitas Sugar Dressing (100% Gula) dalam Meningkatkan Kepadatan Kolagen pada Proses Penyembuhan Luka Bakar Buatan pada Kulit Tikus Putih (Rattus norvegicus) Jantan. Jurnal Medik Veteriner Vol.1 No.3: 134-141.
Navadiya, S.K., Yagnesh L. Vaghani, Mukesh P. Patel, 2012., Study of Topical Placental Extract Versus Povidone Iodine and Saline Dressing in Various Diabetic Wounds. National Journal of Medical Research. Volume 2: Issue 4.
Arifin, Wan N. dan Wan Mohd Z., 2017. Sample Size Calculation in Animal Studies Using Resource Equation Approach. Malaysia Journal Medical Sciences 24(5): 101-105.
Hazrati, M., D. Mehrabani, A. Japoni, H. Montasery, N. Azarpira, A.R. Hamidian-shirazi, N. Tanideh, 2010. Effect of Honey on Healing of Pseudomonas aeruginosa Infected Burn Wounds in Rat. Journal of Applied Animal Research Res. 37 (2010): 161-165.
Pereira, D.d.S.T.P., Maria Helena M.L.R, Nicodemos Teles d.P.F, Ana Maria d.A.C.L, Maria Tereza d.S.C, 2012. Development of Animal Model for Studying Deep Second-Degree Thermal Burns. Hindawi Publishing Corporation Journal of Biomedicine and Biotechnology Volume 2012, Article ID 460841.
Rastegar, F., N. Azarpira, M. Amiri, A. Azarpira, 2011. The Effect of Egg Yolk Oil in the Healing of Third Degree Burn Wound in Rats. Iran Red Crescent Medical Journal 13(10):739-743.
Hahn, Jurgen B., August B., Heiker B., Irina E., Stefan K., Maila R., Valentina S., Nadja Z., 2014. CELLULAR RESPONSES TO EGG-OIL (CHARISMON©). ACTA MEDICA (Hradec Králové).
Chakraborty, P.D., De D., Bandyopadhyay S., Bhattacharyya D., 2009. Human aqueous placental extract as a wound healer. Journal of wound care
Kovalcuks, Aleksandrs, 2015. Comparison of Bioactive Compound Content in Egg Yolk Oil Extracted from Eggs Obtained from Different Laying Hen Housing Systems. World Academy of Science, Engineering and Technology International Journal of Nutrition and Food Engineering
Lin, Teoh S., Azian A.L., Noor A.A.H., Wan Z.W.N., Musalmah M., 2012. Evaluation of Topical Tocopherol Cream on Cutaneous Wound Healing in Streptozotocin-Induced Diabetic Rats. Hindawi Publishing Corporation
Hong, Jong Won, Won Jai Lee, Seung Boem Hahn, Bom Jin Kim, Dae Hyun Lew, 2010. The Effect of Human Placenta Extract in a Wound Healing Model. Annals of Plastic Surgery, volume 65
Silva, Jessica R., Beatriz B., Carolina M.C.K., Thamiris C., Mariah B.P.A., Hosana G.R., 2018. Wound Healing and Omega-6 Fatty Acids: From Inflamation to Repair. Hindawi Publishing Corporation
Lee, K. C., Kavita Joory, Naiem S. Moiemen, 2014. History of burns: The past, present and the future. Burns & Trauma, October 2014, Vol 2, Issue 4.
Setiawan, M. Riza, Afiana Rohmani, Ika Dyah Kurniati, Kanti Ratnaningrum, Rochman Basuki, 2015. Buku Ajar Ilmu Bedah. Fakultas Kedokteran. Universitas Muhammadiyah Semarang.
KalbeMed, 2020. Bioplacenton®. https://kalbemed.com/Products-Diseases/Products/Read-Product-Article/ArtMID/458/ArticleID/179/BIOPLACENTON. Diakses Mei 2020
Hu, T. M., Tsuo-Hung Lan and El-Wui Loh, 2012. An Emerging Complimentary Medicine-Yolk Oil Made from Heating Method. Journal of Traditional and Complementary Medicine Vol. 2, No. 2, pp. 202-203.
Madan, K. dan Sanju Nanda, 2016. Hen egg yolk oil: A potential source of bioavailable lutein and zeaxanthin for skin and sun protection. World Journal Pharmaceutical Sciences. 5(1): 71-80.
Guo, S. dan L.A. DiPietro, 2010. Factors Affecting Wound Healing. Center for Wound Healing and Tissue Regeneration, Department of Periodontics, College of Dentistry. University of Illinois at Chicago.
Tiwari, V.K., 2019. Burn wound: How it differs from other wounds?. Department of Burns and Plastic Surgery, VMMC and Safdarjung Hospital, New Delhi, India.
Alhasyimi, Ananto A., 2016. INDUKSI RE-EPITELISASI PADA PROSES PENYEMBUHAN LUKA GINGIVA OLEH APLIKASI TOPIKAL EKSTRAK DAUN SAGE (Salvia officinalis L.) KONSENTRASI 50% (Kajian In Vivo Pada Tikus Sprague Dawley. Bagian Ortodonsi, Fkg Universitas Gadjah Mada, Yogyakarta
Gonzales, Ana C.O., Zilton A.A., Tila F.C. Alena R.A.P.M., 2017. Wound healing-A ltiteratire review. Anais Brasileiros de Dermatologia.
Kartikaningtyas, Aqilla T., Prayitno dan Sri P. L., 2015. Pengaruh Aplikasi Gel Ekstrak Kulit Citrus Sinensis terhadap Epitelisasi pada Penyembuhan Luka Gingiva Tikus Sprague Dawley. Majalah Kedokteran Gigi Indonesia.
Nasution, Abdillah I., 2016. BUKU AJAR BIOMOLEKULER untuk Ilmu Kedokteran Dasar. Syiah Kuala University Press
Batthacharya, Geetika K., 2017. Pathology for Dental Students (Second Edition). ELSEVIER.
Serhan, Charles N., Peter A.W., Derek W.G., 2010. Fundamentals of Inflamation. Cambridge University Press.
Anderson, James M., 2013. Inflamation, Wound Healing and the Foreign-Body Response dalam Biomaterials Science (Third Edition). Elsevier Academic Press
Anderson, James M., 2019. Biocompatibility and Bioresponse to Biomaterials dalam Principles of Regenerative Medicine (Third Edition). Elsevier Academic Press
Ivanalee, S. K., Ira Sari Y., Maya Nurwartanti Y., Nusdianto Triakoso, Iwan Sahrial H., Amung Logam S., 2018.
Efektivitas Sugar Dressing (100% Gula) dalam Meningkatkan Kepadatan Kolagen pada Proses Penyembuhan Luka Bakar Buatan pada Kulit Tikus Putih (Rattus norvegicus) Jantan. Jurnal Medik Veteriner Vol.1 No.3: 134-141.
Navadiya, S.K., Yagnesh L. Vaghani, Mukesh P. Patel, 2012., Study of Topical Placental Extract Versus Povidone Iodine and Saline Dressing in Various Diabetic Wounds. National Journal of Medical Research. Volume 2: Issue 4.
Arifin, Wan N. dan Wan Mohd Z., 2017. Sample Size Calculation in Animal Studies Using Resource Equation Approach. Malaysia Journal Medical Sciences 24(5): 101-105.
Hazrati, M., D. Mehrabani, A. Japoni, H. Montasery, N. Azarpira, A.R. Hamidian-shirazi, N. Tanideh, 2010. Effect of Honey on Healing of Pseudomonas aeruginosa Infected Burn Wounds in Rat. Journal of Applied Animal Research Res. 37 (2010): 161-165.
Pereira, D.d.S.T.P., Maria Helena M.L.R, Nicodemos Teles d.P.F, Ana Maria d.A.C.L, Maria Tereza d.S.C, 2012. Development of Animal Model for Studying Deep Second-Degree Thermal Burns. Hindawi Publishing Corporation Journal of Biomedicine and Biotechnology Volume 2012, Article ID 460841.
Rastegar, F., N. Azarpira, M. Amiri, A. Azarpira, 2011. The Effect of Egg Yolk Oil in the Healing of Third Degree Burn Wound in Rats. Iran Red Crescent Medical Journal 13(10):739-743.
Hahn, Jurgen B., August B., Heiker B., Irina E., Stefan K., Maila R., Valentina S., Nadja Z., 2014. CELLULAR RESPONSES TO EGG-OIL (CHARISMON©). ACTA MEDICA (Hradec Králové).
Chakraborty, P.D., De D., Bandyopadhyay S., Bhattacharyya D., 2009. Human aqueous placental extract as a wound healer. Journal of wound care
Kovalcuks, Aleksandrs, 2015. Comparison of Bioactive Compound Content in Egg Yolk Oil Extracted from Eggs Obtained from Different Laying Hen Housing Systems. World Academy of Science, Engineering and Technology International Journal of Nutrition and Food Engineering
Lin, Teoh S., Azian A.L., Noor A.A.H., Wan Z.W.N., Musalmah M., 2012. Evaluation of Topical Tocopherol Cream on Cutaneous Wound Healing in Streptozotocin-Induced Diabetic Rats. Hindawi Publishing Corporation
Hong, Jong Won, Won Jai Lee, Seung Boem Hahn, Bom Jin Kim, Dae Hyun Lew, 2010. The Effect of Human Placenta Extract in a Wound Healing Model. Annals of Plastic Surgery, volume 65
Silva, Jessica R., Beatriz B., Carolina M.C.K., Thamiris C., Mariah B.P.A., Hosana G.R., 2018. Wound Healing and Omega-6 Fatty Acids: From Inflamation to Repair. Hindawi Publishing Corporation